Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 3/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | ARG1 | P05089 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366936 | 0.90 | DPP4 (0.50) | OPRD1DPP4OPRK1SMYD3 | |
| SCHEMBL7364618 | 0.89 | OPRK1 (0.57) | HDAC8OPRD1DPP4OPRK1 | |
| SCHEMBL7360569 | 0.89 | HDAC8 (0.55) | HDAC8OPRD1DPP4OPRK1SMYD3 | |
| SCHEMBL7369343 | 0.86 | DPP4 (0.54) | OPRD1DPP4OPRK1 | |
| SCHEMBL7363744 | 0.85 | OPRD1 (0.61) | HDAC8OPRD1DPP4OPRK1SMYD3 | |
| Hydrochloric Acid SCHEMBL6165142 | 0.82 | HDAC8 (0.61) | HDAC8OPRD1DPP4SMYD3HRH2 | |
| Hydrochloric Acid SCHEMBL6165132 | 0.82 | HDAC8 (0.61) | HDAC8OPRD1DPP4SMYD3HRH2 | |
| SCHEMBL14390395 | 0.80 | HDAC8 (0.67) | HDAC8OPRD1DPP4SMYD3HRH2 | |
| SCHEMBL30429936 | 0.79 | DPP4 (0.60) | HDAC8OPRD1DPP4OPRK1SMYD3 | |
| SCHEMBL7367542 | 0.79 | DPP4 (0.51) | OPRD1DPP4OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |