Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362825 | 0.86 | VCAM1 (0.54) | VCAM1SMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL7368939 | 0.85 | TSHR (0.58) | SMN1; SMN2ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL1285789 | 0.82 | VCAM1 (0.74) | VCAM1SMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL18249786 | 0.80 | VCAM1 (0.66) | VCAM1SMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL7359436 | 0.79 | TP53 (0.57) | SMN1; SMN2HTTALDH1A1MAPTKMT2A | |
| SCHEMBL18249777 | 0.78 | VCAM1 (0.71) | VCAM1SMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL9383490 | 0.77 | MAPT (0.66) | VCAM1SMN1; SMN2HTTALDH1A1MAPT | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL28165768 | 0.77 | VCAM1 (0.74) | VCAM1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL1258621 | 0.77 | VCAM1 (1.00) | VCAM1SMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL18249860 | 0.77 | VCAM1 (0.61) | VCAM1SMN1; SMN2HTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716954-A | ANTIINFLAMMATORY AGENT, ANTIHISTAMINES, IMMUNOSUPPRESSION,AUTOIMMUNE DISEASES | SYNTEX U.S.A. INC. (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0612321-A1 | PYRIDO PYRIDAZINONE AND PYRIDAZINTHIONE COMPOUNDS WITH PDE IV INHIBITING ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993007146-A1 | BENZO AND PYRIDO PYRIDAZINONE AND PYRIDAZINTHIONE COMPOUNDS WITH PDE IV INHIBITING ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1993-04-15 | — | — | WO | disclosed |