Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367028 | 0.86 | FOLH1 (0.55) | FOLH1ANPEPERAP2 | |
| SCHEMBL7440491 | 0.83 | FOLH1 (0.51) | FOLH1ANPEPERAP2 | |
| SCHEMBL7364484 | 0.80 | ANPEP (0.50) | FOLH1ANPEPERAP2 | |
| SCHEMBL7361616 | 0.80 | FOLH1 (0.48) | FOLH1ANPEPERAP2 | |
| SCHEMBL10790731 | 0.79 | ANPEP (0.49) | FOLH1ANPEPERAP2 | |
| SCHEMBL10790739 | 0.79 | ANPEP (0.49) | FOLH1ANPEPERAP2 | |
| SCHEMBL7363389 | 0.79 | FOLH1 (0.49) | FOLH1 | |
| SCHEMBL7367466 | 0.78 | ANPEP (0.47) | FOLH1ANPEPERAP2 | |
| SCHEMBL7363272 | 0.77 | FOLH1 (0.45) | FOLH1ANPEPERAP2 | |
| SCHEMBL7361620 | 0.77 | FOLH1 (0.45) | FOLH1ANPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |