Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230588 | 0.75 | GABRA1 (0.36) | — | |
| SCHEMBL15192199 | 0.75 | — | — | |
| SCHEMBL1651743 | 0.71 | LIPG (0.54) | — | |
| SCHEMBL2690986 | 0.69 | — | — | |
| SCHEMBL5109989 | 0.69 | — | — | |
| SCHEMBL2183638 | 0.69 | — | — | |
| SCHEMBL868397 | 0.69 | MAPT (0.35) | — | |
| SCHEMBL2824560 | 0.68 | CYP2A6 (0.31) | CYP2A6 | |
| SCHEMBL3697681 | 0.67 | — | — | |
| SCHEMBL20829126 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-1019399-A1 | ARYL THIOPHENE DERIVATIVES AS PDE IV INHIBITORS | Merck Frosst Canada & Co. (CA) | 2000-07-19 | — | — | EP | disclosed |
| US-6034089-A | ASTHMA THERAPY | MERCK & CO., INC. (US) | 2000-03-07 | — | — | US | disclosed |
| WO-1999018099-A1 | ARYL THIOPHENE DERIVATIVES AS PDE IV INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 1999-04-15 | — | — | WO | disclosed |