Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366354 | 1.00 | FLT3 (0.44) | FLT3TYRO3MERTKGAS6PPARA | |
| SCHEMBL7368352 | 0.93 | PDE5A (0.50) | FLT3TYRO3MERTKGAS6PPARA | |
| SCHEMBL7368350 | 0.93 | PDE5A (0.50) | FLT3TYRO3MERTKGAS6PPARA | |
| SCHEMBL7365379 | 0.86 | LMNA (0.41) | PPARALMNAMRGPRX4CRHR1HPGD | |
| SCHEMBL7365381 | 0.86 | LMNA (0.41) | PPARALMNAMRGPRX4CRHR1HPGD | |
| SCHEMBL6941312 | 0.84 | MEN1 (0.44) | FLT3TYRO3MERTKGAS6LMNA | |
| SCHEMBL6941310 | 0.84 | MEN1 (0.44) | FLT3TYRO3MERTKGAS6LMNA | |
| SCHEMBL7404535 | 0.84 | PDE5A (0.51) | FLT3TYRO3MERTKGAS6LMNA | |
| SCHEMBL7404538 | 0.84 | PDE5A (0.51) | FLT3TYRO3MERTKGAS6LMNA | |
| SCHEMBL7369160 | 0.84 | PPARA (0.47) | PPARALMNAPDE5AHPGDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |