Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 11/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368350 | 1.00 | PDE5A (0.50) | PDE5AMRGPRX4PPARAPPARGPPARD | |
| SCHEMBL7366354 | 0.93 | FLT3 (0.44) | PDE5AMRGPRX4PPARAPPARGPPARD | |
| SCHEMBL7366356 | 0.93 | FLT3 (0.44) | PDE5AMRGPRX4PPARAPPARGPPARD | |
| SCHEMBL7369160 | 0.91 | PPARA (0.47) | PDE5APPARAPPARGPPARDGAA | |
| SCHEMBL7563607 | 0.87 | PPARA (0.47) | PDE5APPARAPPARGPPARDGAA | |
| SCHEMBL7364151 | 0.87 | PPARA (0.47) | PDE5APPARAPPARGPPARDGAA | |
| SCHEMBL7364158 | 0.87 | PPARA (0.47) | PDE5APPARAPPARGPPARDGAA | |
| SCHEMBL7370786 | 0.86 | MRGPRX4 (0.44) | PDE5AMRGPRX4PPARAPPARGPPARD | |
| SCHEMBL7370784 | 0.86 | MRGPRX4 (0.44) | PDE5AMRGPRX4PPARAPPARGPPARD | |
| SCHEMBL7571098 | 0.86 | CCR2 (0.47) | PDE5APPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |