Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | TP53 | P04637 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366451 | 0.82 | AVPR1A (0.74) | TP53AVPR2AVPR1A | |
| SCHEMBL22650870 | 0.73 | MEN1 (0.60) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL8561545 | 0.72 | MEN1 (0.74) | MEN1KMT2ATP53MAPTAVPR2 | |
| SCHEMBL8770282 | 0.67 | MEN1 (0.85) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL8883555 | 0.67 | AVPR1A (0.76) | MAPTAVPR2AVPR1ASMN1; SMN2RAB9A | |
| SCHEMBL7347384 | 0.66 | AVPR1A (1.00) | AVPR2AVPR1A | |
| SCHEMBL11729204 | 0.66 | MEN1 (0.80) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL6667286 | 0.66 | ALDH1A1 (1.00) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL2047778 | 0.65 | RAB9A (1.00) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL15154820 | 0.64 | RAB9A (0.61) | MEN1KMT2AMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | claimed |
| WO-1996022294-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |