Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 1.00 |
| ▸ | LTA4H | P09960 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.71 |
| ▸ | CCR3 | P51677 | 1/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.68 |
| ▸ | HRH1 | P35367 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091557 | 0.98 | SIGMAR1 (1.00) | SIGMAR1LTA4HSLC6A3CCR3GRIN2B | |
| SCHEMBL492561 | 0.98 | SIGMAR1 (1.00) | SIGMAR1LTA4HSLC6A3CCR3GRIN2B | |
| SCHEMBL8935099 | 0.98 | SIGMAR1 (0.96) | SIGMAR1LTA4HSLC6A3CCR3GRIN2B | |
| Hydrochloric Acid SCHEMBL11555128 | 0.96 | SIGMAR1 (0.96) | SIGMAR1LTA4HSLC6A3CCR3GRIN2B | |
| SCHEMBL10601122 | 0.96 | SIGMAR1 (0.96) | SIGMAR1LTA4HSLC6A3CCR3GRIN2B | |
| SCHEMBL28881215 | 0.96 | SIGMAR1 (0.93) | SIGMAR1LTA4HSLC6A3CCR3GRIN2B | |
| SCHEMBL113897 | 0.96 | SIGMAR1 (0.96) | SIGMAR1LTA4HSLC6A3CCR3GRIN2B | |
| SCHEMBL5302082 | 0.92 | LTA4H (0.86) | SIGMAR1LTA4HSLC6A3CCR3GRIN2B | |
| SCHEMBL8092982 | 0.92 | SIGMAR1 (0.85) | SIGMAR1CCR3 | |
| SCHEMBL83687 | 0.90 | SIGMAR1 (0.86) | SIGMAR1LTA4HSLC6A3CCR3GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714292-A4 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | CAMBRIDGE NEUROSCIENCE INC (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0714292-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1996-06-05 | — | — | EP | claimed |
| WO-1995000131-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | CAMBRIDGE NEUROSCIENCE, INCORPORATED (US) | 1995-01-05 | — | — | WO | claimed |