Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.34 |
| ▸ | ITGAV | P06756 | 12/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366556 | 1.00 | F2 (0.36) | F2ITGB3ITGAVITGA2BCXCR4 | |
| SCHEMBL7367618 | 0.92 | F2 (0.36) | F2ITGB3ITGAVITGA2B | |
| SCHEMBL7367620 | 0.92 | F2 (0.36) | F2ITGB3ITGAVITGA2B | |
| SCHEMBL8168513 | 0.77 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL7377515 | 0.76 | ITGB3 (0.36) | F2ITGB3ITGAVITGA2BCXCR4 | |
| SCHEMBL7377522 | 0.76 | ITGB3 (0.36) | F2ITGB3ITGAVITGA2BCXCR4 | |
| SCHEMBL8218081 | 0.75 | GLS (0.34) | F2ITGB3ITGAVITGA2BCXCR4 | |
| SCHEMBL8218084 | 0.75 | F2 (0.33) | F2ITGB3ITGAVITGA2BCXCR4 | |
| SCHEMBL7373177 | 0.72 | ITGB3 (0.43) | F2ITGB3ITGAVITGA2BCXCR4 | |
| SCHEMBL7373174 | 0.72 | ITGB3 (0.43) | F2ITGB3ITGAVITGA2BCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049693-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999026945-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |