Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360526 | 0.83 | NAPRT (0.58) | KDM4EKMT2ACYP19A1CYP2C9NAPRT | |
| SCHEMBL28177089 | 0.77 | KMT2A (0.56) | THRBGAACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL1601592 | 0.77 | LTA4H (0.63) | GAACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL6280463 | 0.75 | GAA (0.65) | KDM4ETHRBGAASMN1; SMN2IDO1 | |
| SCHEMBL20633917 | 0.75 | GAA (0.54) | KDM4ETHRBGAASMN1; SMN2IDO1 | |
| SCHEMBL13268903 | 0.75 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2IDO1HTTKMT2A | |
| SCHEMBL13268901 | 0.75 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2IDO1HTTKMT2A | |
| SCHEMBL19090372 | 0.74 | TDP1 (0.57) | GAACRHBPCRHR2KMT2A | |
| SCHEMBL9475946 | 0.74 | GAA (0.53) | KDM4EGAACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL9475952 | 0.74 | GAA (0.53) | KDM4EGAACRHBPCRHR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993019047-A1 | TETRAHIDROPYRIDINYL (3/4) SUBSTITUED OXIMES HAVING SIGMA RECEPTOR AFFINITY AND THEIR USE IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM CONDITIONS | WARNER-LAMBERT COMPANY (US) | 1993-09-30 | — | — | WO | disclosed |