Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | PTAFR | P25105 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475946 | 1.00 | GAA (0.53) | GAASMN1; SMN2KDM4EESR1CYP19A1 | |
| SCHEMBL7365545 | 0.83 | TBXAS1 (0.49) | SMN1; SMN2KDM4EESR1CYP19A1KMT2A | |
| SCHEMBL7365547 | 0.83 | TBXAS1 (0.49) | SMN1; SMN2KDM4EESR1CYP19A1KMT2A | |
| SCHEMBL7367952 | 0.82 | RAB9A (0.68) | GAASMN1; SMN2PTAFRKMT2ARAB9A | |
| SCHEMBL7399982 | 0.79 | TBXAS1 (0.49) | SMN1; SMN2KDM4EKMT2ARAB9ANPC1 | |
| SCHEMBL28177089 | 0.77 | KMT2A (0.56) | GAASMN1; SMN2PTAFRKMT2ARAB9A | |
| SCHEMBL19090372 | 0.74 | TDP1 (0.57) | GAAPTAFRKMT2ACRHBPCRHR2 | |
| SCHEMBL7366589 | 0.74 | KDM4E (0.50) | GAASMN1; SMN2KDM4ECYP19A1KMT2A | |
| SCHEMBL6280463 | 0.72 | GAA (0.65) | GAASMN1; SMN2KDM4EKMT2ARAB9A | |
| SCHEMBL13268902 | 0.72 | SMN1; SMN2 (0.64) | GAASMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208343-A | Antidepressants, antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |