Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223727 | 0.84 | PTGS1 (0.72) | HDAC1HDAC3ALDH1A1RAB9APTGS1 | |
| SCHEMBL6656632 | 0.79 | MAPK13 (0.73) | GAAHDAC1HDAC3ALDH1A1RAB9A | |
| SCHEMBL14438185 | 0.76 | POLB (0.81) | GAAHDAC1HDAC3ALDH1A1RAB9A | |
| SCHEMBL6171308 | 0.76 | RAB9A (0.60) | GAAHDAC1HDAC3ALDH1A1RAB9A | |
| SCHEMBL5224950 | 0.75 | RAB9A (0.68) | GAAHDAC1ALDH1A1RAB9APTGS1 | |
| SCHEMBL7291942 | 0.75 | RAB9A (0.64) | GAAHDAC1HDAC3ALDH1A1RAB9A | |
| SCHEMBL28172416 | 0.74 | PTGS2 (0.70) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL12963543 | 0.74 | PTGS1 (0.70) | HDAC1HDAC3ALDH1A1RAB9APTGS1 | |
| SCHEMBL6585730 | 0.73 | CA1 (0.59) | GAAHDAC1HDAC3ALDH1A1RAB9A | |
| SCHEMBL7302098 | 0.73 | PDCD1 (0.68) | ALDH1A1RAB9ANPC1GLAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |