Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298598 | 0.74 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL6209372 | 0.73 | PIK3CD (0.35) | PIK3CDALDH1A1 | |
| SCHEMBL8160692 | 0.72 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL8229956 | 0.70 | MEN1 (0.52) | DPP4DPP8DPP9ALDH1A1 | |
| Succinamide SCHEMBL28754551 | 0.69 | ALOX15 (0.43) | DPP4DPP8DPP9ALDH1A1 | |
| SCHEMBL19552784 | 0.68 | HRH3 (0.43) | — | |
| SCHEMBL7280161 | 0.68 | ALDH1A1 (0.39) | DPP4DPP8DPP9ALDH1A1 | |
| SCHEMBL24024003 | 0.67 | DPP4 (0.37) | DPP4DPP8DPP9ALDH1A1 | |
| SCHEMBL743998 | 0.67 | CYP2D6 (0.48) | ALDH1A1 | |
| SCHEMBL8369998 | 0.67 | ALDH1A1 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763621-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-06-09 | — | — | US | claimed |
| EP-1028716-A1 | METHOD FOR TREATING AND PREVENTING HEART FAILURE AND VENTRICULAR DILATATION | WARNER-LAMBERT COMPANY (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1998025597-A2 | METHOD FOR TREATING AND PREVENTING HEART FAILURE AND VENTRICULAR DILATATION | WARNER-LAMBERT COMPANY (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0777646-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-06-11 | — | — | EP | disclosed |