Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369283 | 0.89 | NOX1 (0.59) | NPY5RKDM4EALDH1A1HPGDTLR8 | |
| SCHEMBL27692931 | 0.89 | NPY5R (0.47) | NPY5RKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL7369244 | 0.89 | GAA (0.55) | NPY5RKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL27674785 | 0.89 | CYP11B1 (0.48) | NPY5RKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL7369700 | 0.87 | NPY5R (0.46) | NPY5RKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL7365284 | 0.85 | PDGFRB (0.51) | NPY5RKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7370361 | 0.84 | TLR8 (0.59) | NPY5RKDM4EALDH1A1HPGDNPC1 | |
| Hydrochloric Acid SCHEMBL7400891 | 0.83 | TLR8 (0.58) | NPY5RKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL7366314 | 0.83 | MAPK13 (0.54) | NPY5RKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL7370040 | 0.82 | TUBB4A (0.48) | NPY5RKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |