Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.59 |
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369244 | 0.91 | GAA (0.55) | NOX1SMPD3CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7366807 | 0.89 | NPY5R (0.59) | NPY5RKDM4EALDH1A1HPGDMKNK1 | |
| SCHEMBL7369700 | 0.84 | NPY5R (0.46) | NOX1NPY5RKDM4EALDH1A1HPGD | |
| SCHEMBL27674785 | 0.84 | CYP11B1 (0.48) | NPY5RKDM4EALDH1A1HPGDTUBB4A | |
| SCHEMBL27692931 | 0.84 | NPY5R (0.47) | NPY5RKDM4EALDH1A1HPGDTUBB4A | |
| SCHEMBL7368735 | 0.83 | SMPD3 (0.52) | NOX1SMPD3NPY5RKDM4EALDH1A1 | |
| SCHEMBL7370258 | 0.81 | MKNK1 (0.46) | CYP1A1CYP1A2CYP1B1NPY5RTUBB4A | |
| SCHEMBL7366314 | 0.80 | MAPK13 (0.54) | NOX1CYP1A2NPY5RKDM4EALDH1A1 | |
| SCHEMBL7365284 | 0.80 | PDGFRB (0.51) | CYP1A1CYP1A2CYP1B1NPY5RKDM4E | |
| SCHEMBL7370040 | 0.80 | TUBB4A (0.48) | SMPD3NPY5RKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |