Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960913 | 0.85 | SMN1; SMN2 (0.64) | TSHRPOLBTDP1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL7427148 | 0.84 | SMN1; SMN2 (0.62) | TSHRPOLBTDP1SMN1; SMN2MAPT | |
| SCHEMBL20903627 | 0.81 | TSHR (0.55) | TSHRPOLBTDP1SMN1; SMN2KMT2A | |
| SCHEMBL19919908 | 0.81 | TSHR (0.55) | TSHRPOLBTDP1SMN1; SMN2KMT2A | |
| SCHEMBL6709378 | 0.80 | TSHR (0.50) | TSHRPOLBTDP1SMN1; SMN2KMT2A | |
| SCHEMBL15025226 | 0.79 | POLB (0.49) | TSHRPOLBTDP1SMN1; SMN2KMT2A | |
| SCHEMBL739486 | 0.79 | TSHR (0.66) | TSHRPOLBTDP1MAPTKMT2A | |
| SCHEMBL1723877 | 0.78 | TSHR (0.51) | TSHRPOLBTDP1SMN1; SMN2MAPT | |
| SCHEMBL6712789 | 0.78 | TDP1 (0.53) | TSHRPOLBTDP1SMN1; SMN2KMT2A | |
| SCHEMBL84933 | 0.77 | TSHR (0.59) | TSHRPOLBTDP1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670497-A | RETROVIRAL PROTEASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0708760-A1 | CYCLIC HYDRAZINE COMPOUNDS | Novartis AG (CH) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002582-A1 | CYCLIC HYDRAZINE COMPOUNDS | CIBA-GEIGY AG (CH) | 1995-01-26 | — | — | WO | disclosed |