Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20903627 | 1.00 | TSHR (0.55) | TSHRALDH1A1POLBTDP1BCHE | |
| SCHEMBL6709378 | 0.87 | TSHR (0.50) | TSHRPOLBTDP1BCHEACHE | |
| SCHEMBL6960913 | 0.86 | SMN1; SMN2 (0.64) | TSHRALDH1A1POLBTDP1BCHE | |
| SCHEMBL13349454 | 0.86 | SMN1; SMN2 (0.51) | ALDH1A1BCHEACHESMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL7427148 | 0.85 | SMN1; SMN2 (0.62) | TSHRALDH1A1POLBTDP1BCHE | |
| SCHEMBL1723877 | 0.85 | TSHR (0.51) | TSHRPOLBTDP1BCHEACHE | |
| SCHEMBL6712789 | 0.85 | TDP1 (0.53) | TSHRALDH1A1POLBTDP1BCHE | |
| SCHEMBL7369878 | 0.83 | TSHR (0.47) | TSHRALDH1A1POLBTDP1BCHE | |
| SCHEMBL10602511 | 0.82 | TSHR (0.49) | TSHRALDH1A1POLBTDP1BCHE | |
| SCHEMBL7366845 | 0.81 | TSHR (0.50) | TSHRPOLBTDP1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108383804-A | The crystal form of neurotrophin simulated compound and its salt | 特罗菲克斯制药股份有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-104761515-B | The crystal formation of neurotrophin simulated compound and its salt | 特罗菲克斯制药股份有限公司 | 2018-03-09 | — | — | CN | disclosed |
| WO-2018039641-A1 | METHODS AND COMPOUNDS FOR TREATING ALCOHOL USE DISORDERS AND ASSOCIATED DISEASES | PHARMATROPHIX, INC. (US) | 2018-03-01 | — | — | WO | disclosed |