Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19317523 | 0.93 | L3MBTL1 (0.68) | L3MBTL1LMNAMAPTTDP1MMP1 | |
| SCHEMBL19317525 | 0.93 | L3MBTL1 (0.68) | L3MBTL1LMNAMAPTTDP1MMP1 | |
| SCHEMBL19305819 | 0.93 | L3MBTL1 (0.68) | L3MBTL1LMNAMAPTTDP1MMP1 | |
| SCHEMBL19317522 | 0.93 | L3MBTL1 (0.68) | L3MBTL1LMNAMAPTTDP1MMP1 | |
| SCHEMBL19317519 | 0.93 | L3MBTL1 (0.68) | L3MBTL1LMNAMAPTTDP1MMP1 | |
| SCHEMBL10534992 | 0.93 | L3MBTL1 (0.68) | L3MBTL1LMNAMAPTTDP1MMP1 | |
| SCHEMBL19317524 | 0.93 | L3MBTL1 (0.68) | L3MBTL1LMNAMAPTTDP1MMP1 | |
| SCHEMBL19317521 | 0.92 | MMP1 (0.68) | L3MBTL1LMNAMAPTTDP1MMP1 | |
| SCHEMBL19317520 | 0.88 | MMP1 (0.68) | L3MBTL1LMNAMAPTTDP1MMP1 | |
| SCHEMBL7563621 | 0.86 | HSD17B3 (0.61) | L3MBTL1LMNAMAPTTDP1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724577-A1 | HETEROCYCLIC AMINES FOR TREATING ISCHAEMIC STROKES | SMITHKLINE BEECHAM PLC (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011238-A1 | HETEROCYCLIC AMINES FOR TREATING ISCHAEMIC STROKES | SMITHKLINE BEECHAM PLC (GB) | 1995-04-27 | — | — | WO | disclosed |