Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368571 | 0.85 | CTDSP1 (0.56) | PKMLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5412652 | 0.74 | KMT2A (0.52) | PKMLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6792419 | 0.73 | KMT2A (0.88) | PKMLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL5422670 | 0.72 | KMT2A (0.64) | PKMLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8003156 | 0.71 | F10 (0.61) | PKMKMT2AMEN1RAB9AF2 | |
| SCHEMBL6895006 | 0.71 | PKM (0.48) | PKMLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL18134604 | 0.71 | MCOLN3 (0.83) | PKMLMNASMN1; SMN2HTTKMT2A | |
| Hydrochloric Acid SCHEMBL6896958 | 0.71 | F10 (0.61) | PKMKMT2AMEN1RAB9AF2 | |
| SCHEMBL10424718 | 0.70 | PKM (0.65) | PKMLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7997631 | 0.70 | F10 (0.63) | F2F10PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211183-B1 | PIPERAZINE DERIVATIVE ANTICOAGULANTS; ANTIISCHEMIC AGENTS; CARDIOVASCULAR DISORDERS | COR THERAPEUTICS, INC. | 2001-04-03 | — | — | US | disclosed |
| EP-0975625-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046591-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |