Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.63 |
| ▸ | PLG | P00747 | 5/20 | 0.62 |
| ▸ | PROC | P04070 | 2/20 | 0.62 |
| ▸ | F2 | P00734 | 7/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999868 | 0.93 | F10 (0.74) | F10PLGPROCF2 | |
| Hydrochloric Acid SCHEMBL6895363 | 0.92 | F10 (0.73) | F10PLGPROCF2 | |
| SCHEMBL7996139 | 0.91 | F10 (0.54) | F10PLGPROCF2 | |
| SCHEMBL7986939 | 0.90 | F10 (0.66) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8003156 | 0.90 | F10 (0.61) | F10PLGPROCF2PRSS1 | |
| SCHEMBL1651311 | 0.90 | F10 (0.65) | F10PLGPROCF2PRSS1 | |
| Hydrochloric Acid SCHEMBL6896958 | 0.89 | F10 (0.61) | F10PLGPROCF2PRSS1 | |
| SCHEMBL7999713 | 0.88 | F10 (0.62) | F10PLGPROCF2 | |
| SCHEMBL7997638 | 0.88 | F10 (0.61) | F10PLGPROCF2PRSS1 | |
| SCHEMBL7996275 | 0.87 | F10 (0.58) | F10PLGPROCF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |