SCHEMBL7366961

SCHEMBL7366961

CC(C)(C)CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)c1ncc[nH]1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.48
PGC P20142 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7374861 0.90 REN (0.60) RENPGC
SCHEMBL7309924 0.90 REN (0.55) RENPGC
SCHEMBL7314662 0.90 REN (0.55) RENPGC
SCHEMBL7369515 0.90 REN (0.56) REN
SCHEMBL7293684 0.89 REN (0.50) REN
Acetic Acid SCHEMBL7326759 0.89 REN (0.54) RENPGC
SCHEMBL7367557 0.89 REN (0.52) REN
SCHEMBL7381237 0.87 REN (0.52) REN
SCHEMBL7365628 0.87 REN (0.54) REN
SCHEMBL7432435 0.87 REN (0.52) RENPGC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0231919-A2 N-Heterocyclic alcohol renin inhibitors E.R. Squibb & Sons, Inc. (US) 1987-08-12 EP disclosed