Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369515 | 0.95 | REN (0.56) | REN | |
| SCHEMBL7293684 | 0.92 | REN (0.50) | REN | |
| SCHEMBL7381238 | 0.90 | REN (0.43) | REN | |
| SCHEMBL7367557 | 0.90 | REN (0.52) | REN | |
| SCHEMBL7387590 | 0.89 | REN (0.59) | REN | |
| SCHEMBL7376536 | 0.89 | REN (0.50) | REN | |
| SCHEMBL7300714 | 0.88 | REN (0.47) | REN | |
| SCHEMBL7365628 | 0.88 | REN (0.54) | REN | |
| SCHEMBL7309924 | 0.87 | REN (0.55) | REN | |
| SCHEMBL7366961 | 0.87 | REN (0.48) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055466-A | Renin inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1991-10-08 | — | — | US | disclosed |