Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945540 | 0.90 | YAP1 (0.59) | YAP1IRAK4CHEK1CHEK2 | |
| SCHEMBL15635836 | 0.90 | YAP1 (0.56) | YAP1IRAK4CCNCCDK8CLK1 | |
| SCHEMBL7370553 | 0.86 | YAP1 (0.45) | YAP1IRAK4CCNCCDK8CLK1 | |
| SCHEMBL7370214 | 0.86 | YAP1 (0.45) | YAP1IRAK4CCNCCDK8CLK1 | |
| SCHEMBL7367463 | 0.86 | HSP90AA1 (0.44) | HSP90AA1SCN9A | |
| SCHEMBL7367462 | 0.86 | HSP90AA1 (0.44) | HSP90AA1SCN9A | |
| SCHEMBL17363152 | 0.80 | YAP1 (0.47) | YAP1IRAK4CCNCCDK8CLK1 | |
| SCHEMBL6940663 | 0.77 | MAPT (0.52) | YAP1HSP90AA1 | |
| SCHEMBL6941192 | 0.77 | MAPT (0.52) | YAP1HSP90AA1 | |
| SCHEMBL7404179 | 0.76 | PDE5A (0.48) | PDE5ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |