Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367462 | 1.00 | HSP90AA1 (0.44) | HSP90AA1CDK2MAP2K1PRKCQALB | |
| SCHEMBL15638342 | 0.89 | HCAR3 (0.46) | CDK2MAP2K1ALBHCAR3 | |
| SCHEMBL6946805 | 0.89 | NPC1 (0.47) | CDK2MAP2K1ALBHCAR3 | |
| SCHEMBL7367414 | 0.86 | YAP1 (0.48) | HSP90AA1SCN9A | |
| SCHEMBL7185729 | 0.79 | KDM4E (0.47) | HSP90AA1PRKCQPIM1 | |
| SCHEMBL7185735 | 0.79 | KDM4E (0.47) | HSP90AA1PRKCQPIM1 | |
| SCHEMBL15635242 | 0.78 | MAP2K1 (0.48) | MAP2K1HCAR3 | |
| SCHEMBL8300943 | 0.77 | ALB (0.47) | CDK2MAP2K1ALB | |
| SCHEMBL7185961 | 0.76 | HCAR3 (0.56) | HCAR3 | |
| SCHEMBL7185959 | 0.76 | HCAR3 (0.56) | HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |