Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27674807 | 0.89 | LMNA (0.30) | TSHRLMNA | |
| SCHEMBL11814630 | 0.89 | TSHR (0.42) | TSHRTHRBFDPS | |
| SCHEMBL28049438 | 0.87 | TSHR (0.33) | TSHRTHRBFDPS | |
| SCHEMBL27674724 | 0.79 | TSHR (0.38) | TSHRTHRBFDPS | |
| SCHEMBL56177 | 0.77 | — | — | |
| SCHEMBL9171978 | 0.74 | TSHR (0.39) | TSHRLMNAFDPS | |
| SCHEMBL6902592 | 0.74 | TSHR (0.39) | TSHRLMNATHRBFDPS | |
| SCHEMBL27508748 | 0.72 | — | — | |
| SCHEMBL4620362 | 0.71 | — | — | |
| SCHEMBL3409360 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722436-A4 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0722436-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009833-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |