Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 5/20 | 0.40 |
| ▸ | TLR4 | O00206 | 3/20 | 0.39 |
| ▸ | TLR2 | O60603 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796992 | 0.86 | NPC1 (0.55) | CA12CA1CA2CA9KDM1A | |
| SCHEMBL6796987 | 0.86 | NPC1 (0.55) | CA12CA1CA2CA9KDM1A | |
| SCHEMBL6796866 | 0.85 | CYP19A1 (0.47) | CA12CA1CA2CA9TLR4 | |
| SCHEMBL6796859 | 0.85 | CYP19A1 (0.47) | CA12CA1CA2CA9TLR4 | |
| SCHEMBL7366274 | 0.84 | CA12 (0.40) | CA12CA1CA2CA9KDM1A | |
| SCHEMBL7367589 | 0.83 | MMP1 (0.45) | KDM1AEGFR | |
| SCHEMBL6799851 | 0.82 | NPC1 (0.50) | CA12CA1CA2CA9KDM1A | |
| SCHEMBL6793309 | 0.82 | TLR4 (0.47) | CA12CA1CA2CA9TLR4 | |
| SCHEMBL6793312 | 0.82 | TLR4 (0.47) | CA12CA1CA2CA9TLR4 | |
| SCHEMBL6799845 | 0.82 | NPC1 (0.50) | CA12CA1CA2CA9KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874845-A1 | PYRIDO (2,3-B) PYRAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024355-A1 | PYRIDO (2,3-B) PYRAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |