Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP3 | P08254 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23190984 | 0.88 | MMP2 (0.56) | MTNR1AMTNR1BMMP2MMP3MMP9 | |
| SCHEMBL28932705 | 0.84 | MMP2 (0.55) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7870421 | 0.80 | MMP2 (0.50) | MTNR1AMTNR1BMMP2MMP3MMP9 | |
| SCHEMBL13535268 | 0.77 | MTNR1A (0.48) | MTNR1AMTNR1BMMP2MMP3MMP9 | |
| SCHEMBL6896649 | 0.77 | MTNR1A (0.51) | MTNR1AMTNR1BMMP2MMP3MMP9 | |
| SCHEMBL6896645 | 0.77 | MTNR1A (0.51) | MTNR1AMTNR1BMMP2MMP3MMP9 | |
| SCHEMBL7368245 | 0.77 | MTNR1A (0.59) | MTNR1AMTNR1BMMP2MMP3MMP9 | |
| SCHEMBL8500821 | 0.75 | CYP1A2 (0.53) | CYP1A2ALDH1A1PPARG | |
| SCHEMBL8500824 | 0.75 | CYP1A2 (0.53) | CYP1A2ALDH1A1PPARG | |
| SCHEMBL5695682 | 0.75 | TSHR (0.46) | CYP1A2MEN1KMT2AALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790974-A1 | SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BIARYLPENTANOIC ACIDS AND DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITIORS | Bayer Corporation (US) | 1997-08-27 | — | — | EP | claimed |
| WO-1996015096-A1 | SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BIARYLPENTANOIC ACIDS AND DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITIORS | BAYER CORPORATION (US) | 1996-05-23 | — | — | WO | claimed |