Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.53 |
| ▸ | GCK | P35557 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367594 | 1.00 | RAB9A (0.61) | RAB9AMEN1KMT2AGAACYP1A2 | |
| SCHEMBL9376091 | 0.86 | CYP1A2 (0.72) | RAB9AMEN1KMT2AGAACYP1A2 | |
| SCHEMBL9376095 | 0.86 | CYP1A2 (0.72) | RAB9AMEN1KMT2AGAACYP1A2 | |
| SCHEMBL7491966 | 0.80 | ALDH1A1 (0.47) | GAACYP1A2NPC1ALDH1A1CYP19A1 | |
| SCHEMBL7491959 | 0.80 | ALDH1A1 (0.47) | GAACYP1A2NPC1ALDH1A1CYP19A1 | |
| SCHEMBL7367425 | 0.78 | MAPT (0.46) | RAB9AMEN1KMT2AGAACYP1A2 | |
| SCHEMBL7367418 | 0.78 | MAPT (0.46) | RAB9AMEN1KMT2AGAACYP1A2 | |
| SCHEMBL9648715 | 0.78 | CYP1A2 (0.58) | MEN1KMT2AGAACYP1A2ALDH1A1 | |
| SCHEMBL9648701 | 0.78 | CYP1A2 (0.58) | MEN1KMT2AGAACYP1A2ALDH1A1 | |
| SCHEMBL4733272 | 0.76 | KMT2A (0.73) | RAB9AMEN1KMT2AGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874845-B1 | PYRIDO (2,3-B) PYRAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6117875-A | Pyrido (2,3-B) pyrazine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-0874845-A1 | PYRIDO (2,3-B) PYRAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024355-A1 | PYRIDO (2,3-B) PYRAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |