Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505080 | 0.88 | GRIN2B (0.59) | GRIN1GRIN2BGRIN2DGRIN3BADRA1D | |
| Hydrochloric Acid SCHEMBL5974096 | 0.87 | GRIN2B (0.58) | GRIN1GRIN2BGRIN2DGRIN3BADRA1D | |
| SCHEMBL5974310 | 0.83 | ALDH1A1 (0.49) | MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL5974263 | 0.83 | MAPK1 (0.42) | MAPK1ALDH1A1OPRM1MEN1KMT2A | |
| SCHEMBL5505091 | 0.83 | ALDH1A1 (0.49) | MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL5502026 | 0.83 | ALDH1A1 (0.49) | MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL5509796 | 0.80 | ALDH1A1 (0.56) | MAPK1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5974434 | 0.79 | ALDH1A1 (0.55) | MAPK1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7405065 | 0.76 | TMEM97 (0.62) | KDM4EGRIN1GRIN2BGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL7406531 | 0.75 | TMEM97 (0.61) | OPRM1GRIN1GRIN2BGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189886-A1 | ETHANESULFONYL-PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-27 | — | — | EP | claimed |
| WO-2000075109-A1 | ETHANESULFONYL-PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-14 | — | — | WO | claimed |