Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.60 |
| ▸ | CES1 | P23141 | 2/20 | 0.60 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 14/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 14/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 14/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 14/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 14/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160527 | 0.85 | FAAH (0.46) | FAAHCES1NCEH1HDAC3HDAC4 | |
| SCHEMBL21645499 | 0.83 | FAAH (0.83) | FAAHCES1NCEH1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL21645495 | 0.81 | FAAH (0.81) | FAAHCES1NCEH1HDAC3HDAC4 | |
| SCHEMBL7371238 | 0.81 | FAAH (0.68) | FAAHCES1NCEH1HDAC3HDAC4 | |
| SCHEMBL7444620 | 0.81 | FAAH (0.81) | FAAHCES1NCEH1HDAC3HDAC4 | |
| SCHEMBL21645829 | 0.81 | FAAH (0.64) | FAAHCES1NCEH1HDAC3HDAC4 | |
| SCHEMBL21645557 | 0.76 | HDAC3 (0.58) | FAAHCES1NCEH1HDAC3HDAC4 | |
| SCHEMBL38656879 | 0.75 | HDAC3 (0.63) | FAAHCES1NCEH1HDAC3HDAC4 | |
| SCHEMBL13764125 | 0.75 | FAAH (1.00) | FAAHCES1HDAC3HDAC4HDAC1 | |
| SCHEMBL22015495 | 0.75 | CES1 (0.46) | FAAHCES1NCEH1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020177594-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-11-28 | — | — | US | disclosed |
| US-20020103192-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-08-01 | — | — | US | disclosed |
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103192-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC5, HDAC4 | FAAH 1179/4885CES1 418/4885NCEH1 245/4885 |
| US-20020177594-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC11, HDAC3 | FAAH 2579/4885CES1 451/4885NCEH1 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.