Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.47 |
| ▸ | GRN | P28799 | 2/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.45 |
| ▸ | LAP3 | P28838 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22207962 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL22207963 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL7037584 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL16750034 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL7391076 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL10705609 | 0.84 | FOLH1 (0.51) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL10705602 | 0.84 | FOLH1 (0.51) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL7373627 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL10974177 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL10974215 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MEN1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028716-A1 | METHOD FOR TREATING AND PREVENTING HEART FAILURE AND VENTRICULAR DILATATION | WARNER-LAMBERT COMPANY (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1998025597-A2 | METHOD FOR TREATING AND PREVENTING HEART FAILURE AND VENTRICULAR DILATATION | WARNER-LAMBERT COMPANY (US) | 1998-06-18 | — | — | WO | disclosed |