Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.51 |
| ▸ | MME | P08473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10705609 | 1.00 | FOLH1 (0.51) | FOLH1MMEALDH1A1MEN1LMNA | |
| SCHEMBL10703915 | 0.85 | ALDH1A1 (0.47) | FOLH1MMEALDH1A1MEN1LMNA | |
| SCHEMBL11130452 | 0.85 | ALDH1A1 (0.47) | FOLH1MMEALDH1A1MEN1LMNA | |
| SCHEMBL7367874 | 0.84 | ALDH1A1 (0.57) | FOLH1MMEALDH1A1MEN1LMNA | |
| SCHEMBL22207963 | 0.84 | ALDH1A1 (0.57) | FOLH1MMEALDH1A1MEN1LMNA | |
| SCHEMBL22207962 | 0.84 | ALDH1A1 (0.57) | FOLH1MMEALDH1A1MEN1LMNA | |
| SCHEMBL10705810 | 0.81 | MME (0.44) | FOLH1MMEALDH1A1MEN1LMNA | |
| SCHEMBL11121448 | 0.81 | MME (0.44) | FOLH1MMEALDH1A1MEN1LMNA | |
| SCHEMBL10705010 | 0.78 | GRN (0.39) | FOLH1MMEALDH1A1MEN1KMT2A | |
| SCHEMBL10421717 | 0.77 | TAS1R3 (0.50) | FOLH1MMEALDH1A1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126974-B1 | CARBOXYALKYL PEPTIDE DERIVATIVES | G.D. Searle & Co. (US) | 1988-06-15 | — | — | EP | disclosed |
| US-4511504-A | COLLAGENASE INHIBITORS | G.D. SEARLE & CO. (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0126974-A1 | Carboxyalkyl peptide derivatives | G.D. Searle & Co. (US) | 1984-12-05 | — | — | EP | disclosed |