Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130001 | 0.81 | BIRC2 (0.50) | MMEECE1MMP8 | |
| SCHEMBL7363834 | 0.80 | HRH4 (0.53) | MMEECE1MMP8 | |
| SCHEMBL7363836 | 0.80 | HRH4 (0.53) | MMEECE1MMP8 | |
| SCHEMBL7363831 | 0.80 | HRH4 (0.53) | MMEECE1MMP8 | |
| SCHEMBL11129428 | 0.79 | MME (0.59) | MMEECE1 | |
| SCHEMBL1239980 | 0.78 | POLB (0.52) | MMP8GAA | |
| SCHEMBL4116935 | 0.77 | POLB (0.53) | MMP8GAA | |
| SCHEMBL7364337 | 0.77 | POLB (0.53) | MMP8GAA | |
| SCHEMBL7364336 | 0.77 | POLB (0.53) | MMP8GAA | |
| SCHEMBL10645951 | 0.76 | OPRD1 (0.54) | CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |