Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 9/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407567 | 0.74 | ALOX12 (0.41) | ESR1ESR2ALOX15ALOX12KDM4E | |
| SCHEMBL23841449 | 0.71 | TYR (0.41) | ESR1ESR2ALOX15ALOX12NR3C1 | |
| SCHEMBL11529244 | 0.69 | CYP3A4 (0.42) | MCL1ESR1ESR2ALOX15ALOX12 | |
| SCHEMBL7115820 | 0.69 | AKR1B1 (0.40) | BCL2BCL2L1MCL1BCL2L2ESR1 | |
| SCHEMBL282461 | 0.69 | ESR1 (0.39) | ESR1ESR2NR3C1PGRNR3C2 | |
| SCHEMBL14647773 | 0.67 | GABRA1 (0.45) | BCL2BCL2L1MCL1BCL2L2ESR1 | |
| SCHEMBL5379461 | 0.67 | CYP3A4 (0.48) | BCL2BCL2L1MCL1BCL2L2ALOX15 | |
| SCHEMBL476694 | 0.66 | CYP3A4 (0.58) | ESR1ESR2ALOX15ALOX12CYP3A4 | |
| SCHEMBL2018825 | 0.66 | ESR2 (0.47) | ESR1ESR2ALOX15CYP3A4TDP1 | |
| SCHEMBL16018022 | 0.66 | CYP3A4 (0.42) | ESR1ALOX15CYP3A4SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991618-A4 | SELECTIVE THYROID HORMONE ANALOGS | UNIV CALIFORNIA (US) | 2000-09-27 | — | — | EP | disclosed |
| EP-0991618-A1 | SELECTIVE THYROID HORMONE ANALOGS | The Regents of the University of California (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057919-A1 | SELECTIVE THYROID HORMONE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-12-23 | — | — | WO | disclosed |