Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449177 | 0.84 | ALDH1A1 (0.40) | HRH3HRH4CYP3A4 | |
| SCHEMBL19975547 | 0.80 | HRH3 (0.43) | HRH3HRH4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6801136 | 0.75 | LMNA (0.54) | LMNAHRH3HRH4CYP1A2CYP3A4 | |
| SCHEMBL7158594 | 0.71 | — | — | |
| SCHEMBL7300956 | 0.71 | CYP3A4 (0.53) | HRH3HRH4CYP3A4 | |
| SCHEMBL9540186 | 0.71 | LMNA (0.46) | LMNACYP1A2CYP3A4L3MBTL1 | |
| SCHEMBL7374428 | 0.70 | LMNA (0.44) | LMNACYP1A2CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL7979485 | 0.69 | ELANE (0.49) | LMNACYP1A2CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL6209531 | 0.69 | KMT2A (0.65) | LMNACYP1A2CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL1331771 | 0.68 | MEN1 (0.38) | HRH3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073638-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054304-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |