Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.48 |
| ▸ | F10 | P00742 | 8/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.46 |
| ▸ | F7 | P08709 | 3/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | PLAT | P00750 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7363171 | 0.95 | F2 (0.51) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7368632 | 0.87 | F2 (0.51) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7362150 | 0.81 | F2 (0.57) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7360775 | 0.80 | F2 (0.53) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7360126 | 0.76 | F2 (0.71) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7368094 | 0.75 | CA1 (0.38) | — | |
| Trifluoroacetic Acid SCHEMBL7454428 | 0.74 | F2 (0.74) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7364863 | 0.73 | F2 (0.50) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7363925 | 0.72 | F2 (0.53) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7459282 | 0.72 | F2 (0.62) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |