Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251345 | 0.84 | ADRB2 (0.71) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL2024020 | 0.80 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL2024023 | 0.80 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL2024026 | 0.80 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL9654030 | 0.80 | ADRB1 (0.82) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL7367538 | 0.79 | MEN1 (0.62) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7364771 | 0.79 | MEN1 (0.62) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7367855 | 0.78 | MEN1 (0.63) | ADRB2ADRB1ADRB3 | |
| SCHEMBL2020023 | 0.77 | KCNH2 (0.78) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL2020025 | 0.77 | KCNH2 (0.78) | ADRB2ADRB1ADRB3KCNH2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |