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SCHEMBL7368396

SCHEMBL7368396

CCCCC[C@H](CC(=O)NOCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MMP1 P03956 11/20 0.58
▸ FCER2 P06734 1/20 0.58
▸ BIRC2 Q13490 1/20 0.57
▸ MMP2 P08253 17/20 0.55
▸ MMP3 P08254 12/20 0.55
▸ MMP7 P09237 6/20 0.55
▸ REN P00797 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7368398 1.00 MMP1 (0.58) MMP1FCER2BIRC2MMP2MMP3
SCHEMBL7368588 0.92 BIRC2 (0.51) MMP1FCER2BIRC2MMP2MMP3
SCHEMBL7368591 0.92 BIRC2 (0.51) MMP1FCER2BIRC2MMP2MMP3
SCHEMBL7374482 0.90 MMP1 (0.72) MMP1FCER2BIRC2MMP2MMP3
SCHEMBL7368615 0.89 MMP1 (0.74) MMP1FCER2BIRC2MMP2MMP3
SCHEMBL7368611 0.89 MMP1 (0.74) MMP1FCER2BIRC2MMP2MMP3
SCHEMBL7368616 0.89 MMP1 (0.74) MMP1FCER2BIRC2MMP2MMP3
SCHEMBL7367696 0.86 MMP1 (0.69) MMP1FCER2BIRC2MMP2MMP3
SCHEMBL7368393 0.82 BIRC2 (0.52) MMP1FCER2BIRC2MMP2MMP3
SCHEMBL7374138 0.79 MMP1 (0.49) MMP1BIRC2MMP2MMP3MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0231081-B1 HYDROXAMIC ACIDS ICI AMERICAS INC. (US) 1993-03-17 — — EP disclosed
US-4771038-A Hydroxamic acids ICI AMERICAS INC. (US) 1988-09-13 — — US disclosed
EP-0231081-A2 Hydroxamic acids ICI AMERICAS INC. (US) 1987-08-05 — — EP disclosed