Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 9/20 | 0.49 |
| ▸ | MMP14 | P50281 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 14/20 | 0.46 |
| ▸ | MMP3 | P08254 | 9/20 | 0.46 |
| ▸ | MMP7 | P09237 | 6/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368591 | 0.87 | BIRC2 (0.51) | MMP1MMP9BIRC2MMP2MMP3 | |
| SCHEMBL7368588 | 0.87 | BIRC2 (0.51) | MMP1MMP9BIRC2MMP2MMP3 | |
| SCHEMBL7370265 | 0.80 | MMP1 (0.57) | MMP1MMP14MMP9BIRC2MMP2 | |
| SCHEMBL7430975 | 0.79 | BIRC2 (0.68) | MMP1MMP14MMP9BIRC2MMP2 | |
| SCHEMBL7430956 | 0.79 | BIRC2 (0.68) | MMP1MMP14MMP9BIRC2MMP2 | |
| SCHEMBL7430963 | 0.79 | BIRC2 (0.68) | MMP1MMP14MMP9BIRC2MMP2 | |
| SCHEMBL7374742 | 0.79 | BIRC2 (0.49) | MMP1BIRC2MMP2MMP3MMP7 | |
| SCHEMBL7368398 | 0.79 | MMP1 (0.58) | MMP1BIRC2MMP2MMP3MMP7 | |
| SCHEMBL7368396 | 0.79 | MMP1 (0.58) | MMP1BIRC2MMP2MMP3MMP7 | |
| SCHEMBL7374135 | 0.79 | BIRC2 (0.44) | MMP1MMP14MMP9BIRC2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231081-B1 | HYDROXAMIC ACIDS | ICI AMERICAS INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4771038-A | Hydroxamic acids | ICI AMERICAS INC. (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0231081-A2 | Hydroxamic acids | ICI AMERICAS INC. (US) | 1987-08-05 | — | — | EP | disclosed |