Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 3/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373717 | 0.91 | NR1H4 (0.57) | FLT3NR1H4PPARDPPARGPPARA | |
| SCHEMBL7365352 | 0.91 | KMT2A (0.50) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL7369674 | 0.85 | RXFP1 (0.46) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL7366495 | 0.82 | FLT3 (0.45) | NPC1RAB9AMEN1KMT2AFLT3 | |
| SCHEMBL7369592 | 0.81 | NR1H4 (0.50) | FLT3NR1H4PPARDPPARGPPARA | |
| SCHEMBL7367977 | 0.81 | JAK2 (0.46) | NPC1RAB9AFLT3CDK2 | |
| SCHEMBL7364651 | 0.81 | NR1H4 (0.45) | NR1H4PPARDPPARGPPARAF10 | |
| SCHEMBL7368569 | 0.80 | RXFP1 (0.55) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL7371977 | 0.80 | NR1H4 (0.46) | RXFP1FLT3NR1H4PPARGPPARA | |
| SCHEMBL7367697 | 0.80 | NR1H4 (0.45) | NR1H4PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| US-6372759-B1 | BLOOD COAGULATION FACTOR XA FOR MAMMALS | ELI LILLY AND COMPANY | 2002-04-16 | — | — | US | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |