Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370555 | 0.91 | NR1H4 (0.59) | RXFP1NR1H4PPARDPPARGPPARA | |
| SCHEMBL7365818 | 0.81 | SCN3A (0.46) | RXFP1NPC1RAB9A | |
| SCHEMBL7368426 | 0.80 | NPC1 (0.54) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7367092 | 0.80 | NR1H4 (0.46) | NR1H4PPARDPPARGPPARAF10 | |
| SCHEMBL6172966 | 0.79 | NR1H4 (0.46) | MEN1KMT2ANR1H4PPARDPPARG | |
| SCHEMBL6169797 | 0.79 | NPC1 (0.61) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7366501 | 0.78 | F10 (0.47) | NR1H4PPARDPPARGPPARAF10 | |
| SCHEMBL7367665 | 0.78 | RAB9A (0.48) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6172523 | 0.78 | RXFP1 (0.55) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7369726 | 0.77 | HTT (0.53) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |