SCHEMBL7368446

SCHEMBL7368446

CN(C(N)=O)c1ccccn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
LIPE Q05469 1/20 0.46
POLQ O75417 1/20 0.44
POLB P06746 2/20 0.43
KMT2A Q03164 3/20 0.42
HTT P42858 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 3/20 0.42
TSHR P16473 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
MCL1 Q07820 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27945127 0.98 LIPE (0.45) CYP2D6CYP2C19LIPEPOLQPOLB
SCHEMBL243741 0.82 POLB (0.51) CYP2D6CYP2C19LIPEPOLQPOLB
SCHEMBL762423 0.82 ALDH1A1 (0.50) CYP2D6CYP2C19LIPEPOLQPOLB
SCHEMBL6644466 0.81 CYP2D6 (0.46) CYP2D6CYP2C19LIPEPOLQPOLB
SCHEMBL761923 0.81 CYP2D6 (0.46) CYP2D6CYP2C19LIPEPOLQPOLB
SCHEMBL10597175 0.81 CYP2D6 (0.46) CYP2D6CYP2C19LIPEPOLQPOLB
SCHEMBL424554 0.81 CYP2D6 (0.46) CYP2D6CYP2C19LIPEPOLQPOLB
Hydrochloric Acid SCHEMBL11804810 0.81 POLB (0.50) CYP2D6CYP2C19LIPEPOLQPOLB
SCHEMBL3726837 0.80 HTT (0.53) CYP2D6CYP2C19POLBKMT2AHTT
SCHEMBL8668737 0.78 TSHR (0.46) POLBKMT2AHTTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998042656-A1 NOVEL COMPOUNDS CYTEL CORPORATION (US) 1998-10-01 WO disclosed