Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.79 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.79 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.79 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.79 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.79 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.79 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.79 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.79 |
| ▸ | FAAH | O00519 | 3/20 | 0.57 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | RXRG | P48443 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416762 | 0.95 | HDAC1 (0.71) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL7365669 | 0.88 | HDAC1 (0.80) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL3054236 | 0.88 | HDAC1 (0.72) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL7371056 | 0.86 | HDAC1 (1.00) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL416678 | 0.84 | HDAC1 (0.69) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL7365351 | 0.84 | HDAC1 (0.69) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL10247702 | 0.83 | HDAC1 (0.64) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL7363589 | 0.81 | HDAC1 (0.65) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL1471366 | 0.78 | FAAH (0.71) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL3041199 | 0.78 | FAAH (0.59) | HDAC1HDAC6HDAC2HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020177594-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-11-28 | — | — | US | disclosed |
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177594-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC11, HDAC3 | HDAC1 1/4885HDAC6 7/4885HDAC2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.