Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.71 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | RXRG | P48443 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368514 | 0.95 | HDAC1 (0.79) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL416678 | 0.89 | HDAC1 (0.69) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL10247702 | 0.87 | HDAC1 (0.64) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL7365669 | 0.83 | HDAC1 (0.80) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL3054236 | 0.82 | HDAC1 (0.72) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL7371056 | 0.82 | HDAC1 (1.00) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL7365351 | 0.81 | HDAC1 (0.69) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL7363589 | 0.78 | HDAC1 (0.65) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL4287001 | 0.76 | RXRA (0.50) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL9248638 | 0.75 | RXRA (0.53) | HDAC1HDAC6HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022054-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2012-01-26 | — | — | US | disclosed |
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066847-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | CELLVIR (FR) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022054-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | HAVCR2, MAVS, EIF2AK2 | HDAC1 1056/4885HDAC6 418/4885HDAC2 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.