Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.40 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.39 |
| ▸ | PIP4K2B | P78356 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169151 | 0.76 | RXFP2 (0.39) | RXFP2PIP4K2APIP4K2BESR1CFTR | |
| SCHEMBL6169978 | 0.75 | RXFP2 (0.51) | RXFP2PIP4K2APIP4K2B | |
| SCHEMBL7667295 | 0.75 | HTR1A (0.32) | TYRO3KIF18A | |
| SCHEMBL6170463 | 0.73 | RXFP2 (0.52) | RXFP2PIP4K2APIP4K2B | |
| SCHEMBL7661475 | 0.71 | MAPT (0.36) | — | |
| SCHEMBL6169142 | 0.70 | RXFP2 (0.38) | RXFP2PIP4K2APIP4K2BESR1IDH1 | |
| SCHEMBL1607103 | 0.68 | PIP4K2A (0.64) | PIP4K2APIP4K2BESR1MAOACYP19A1 | |
| SCHEMBL6169059 | 0.66 | ESR1 (0.56) | ESR1BTK | |
| SCHEMBL7377861 | 0.65 | RXFP2 (0.45) | RXFP2ESR1CFTRGABRA1GABRB1 | |
| SCHEMBL6172046 | 0.65 | RXFP2 (0.54) | RXFP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |