Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661475 | 0.86 | MAPT (0.36) | HTR1AKHKKCNH2 | |
| SCHEMBL6168838 | 0.79 | GPR119 (0.31) | HTR1AHTR7HTR2BHTR6GPR119 | |
| SCHEMBL6168757 | 0.77 | F10 (0.43) | — | |
| SCHEMBL6170090 | 0.77 | F10 (0.41) | — | |
| SCHEMBL6170084 | 0.77 | GPR119 (0.36) | GPR119KIF18A | |
| SCHEMBL7089068 | 0.75 | GPR119 (0.36) | GPR119KIF18A | |
| SCHEMBL7368537 | 0.75 | RXFP2 (0.40) | TYRO3KIF18A | |
| SCHEMBL6168830 | 0.73 | F10 (0.36) | GPR119KIF18A | |
| SCHEMBL6171161 | 0.70 | NR1H4 (0.45) | — | |
| SCHEMBL6173478 | 0.70 | F10 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372759-B1 | BLOOD COAGULATION FACTOR XA FOR MAMMALS | ELI LILLY AND COMPANY | 2002-04-16 | — | — | US | disclosed |