Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339731 | 0.91 | MAPT (0.41) | ALDH1A1POLBSMN1; SMN2RAB9ALMNA | |
| SCHEMBL7368763 | 0.84 | RAB9A (0.43) | ALDH1A1POLBSMN1; SMN2RAB9ALMNA | |
| SCHEMBL7377964 | 0.84 | POLB (0.56) | ALDH1A1POLBSMN1; SMN2RAB9ALMNA | |
| SCHEMBL7374190 | 0.83 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2RAB9ALMNAMAPT | |
| SCHEMBL7371278 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL7370750 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL7371553 | 0.80 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL8442696 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL7338369 | 0.78 | TNF (0.42) | ALDH1A1LMNAMAPTMAPK1KDM4E | |
| SCHEMBL7372163 | 0.77 | RAB9A (0.49) | ALDH1A1POLBSMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |