Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 14/20 | 0.50 |
| ▸ | HTR7 | P34969 | 13/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367430 | 0.89 | DRD2 (0.55) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL7365704 | 0.85 | DRD2 (0.55) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL7360768 | 0.83 | DRD2 (0.52) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL7370352 | 0.81 | DRD2 (0.51) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL7360758 | 0.81 | DRD2 (0.50) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL7366536 | 0.80 | DRD2 (0.49) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL7365734 | 0.80 | HTR2A (0.53) | DRD2SLC6A4HTR2AACHE | |
| SCHEMBL7368296 | 0.80 | DRD2 (0.49) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL7364402 | 0.79 | DRD2 (0.48) | DRD2SLC6A4HTR2AHTR1A | |
| SCHEMBL7366166 | 0.79 | HTR6 (0.52) | DRD2SLC6A4HTR2AHTR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780474-A | ADMINISTERING IN THE TREATMENT OF PSYCHOTIC DISORDERS, ANXIO-DEPRESSIVE DISORDERS AND AGGRESSIVENESS | ADIR ET COMPAGNIE (FR) | 1998-07-14 | — | — | US | disclosed |