Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 14/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829390 | 0.95 | EPHX1 (0.50) | EPHX1ACHEHCAR2RAB9A | |
| SCHEMBL9829396 | 0.95 | EPHX1 (0.50) | EPHX1ACHEHCAR2RAB9A | |
| SCHEMBL3400195 | 0.87 | EPHX1 (0.43) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL9030664 | 0.85 | EPHX1 (0.42) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL19548070 | 0.83 | FPR2 (0.41) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL7368744 | 0.81 | EPHX1 (0.44) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL10476092 | 0.81 | EPHX1 (0.44) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL31759054 | 0.81 | EPHX1 (0.47) | EPHX1ACHEALDH1A1ATMRAB9A | |
| SCHEMBL6318148 | 0.81 | EPHX1 (0.47) | EPHX1ACHEALDH1A1ATM | |
| SCHEMBL2487393 | 0.81 | EPHX1 (0.47) | EPHX1ACHEALDH1A1POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817292-A2 | NOVEL HETEROCYCLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006055184-A2 | NOVEL HETEROCYCLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-26 | — | — | WO | disclosed |