Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 13/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400195 | 0.85 | EPHX1 (0.43) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL5201837 | 0.85 | EPHX1 (0.43) | EPHX1ACHEALDH1A1RAB9APOLB | |
| SCHEMBL7368744 | 0.83 | EPHX1 (0.44) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL10476092 | 0.83 | EPHX1 (0.44) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL9264188 | 0.81 | EPHX1 (0.46) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL19548070 | 0.81 | FPR2 (0.41) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL9829396 | 0.81 | EPHX1 (0.50) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9829390 | 0.81 | EPHX1 (0.50) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2487393 | 0.80 | EPHX1 (0.47) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL5593036 | 0.79 | RAB9A (0.39) | EPHX1ACHEALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |